CE 0373

Technical Information downolad

Ribocross TE®

Ophthalmic solution for Corneal Cross-linking

Ribocross TE® is a patented ophthalmic solution, fit for all CXL protocols. Thanks to its innovative enhancer, Ribocross TE® provides an effective penetration in the whole corneal stroma, even in EPI-ON conditions.

Main features:

  • Applications:
  • EPI-OFF (Dresden Protocol)
  • EPI-ON (Iontophoresis; MEGARIDE)
  • CXL for keratitis treatment
  • Post refractive surgery CXL (PRK; LASIK)
  • Innovative patented formulation
  • Penetration enhancer
  • Hyposmolar
  • Fit for all CXL protocols
  • Can be used in all CXL protocols
  • Unique patented formulation with penetration enhancer
  • Unique patented formulation with penetration enhancer

Advantages:

Ribocross TE comes in a kit containing a syringe filled with 1,5 ml of solution and a cannula needle for application.
Ribocross TE® is applied in combination with an UV-A light source for ophthalmic use.
Apply a drop every 30 seconds for 10 minutes with the dispenser. Soak corneal surface with saline solution after the first phase. Notice if the cornea is slightly fluorescent with blue light before proceeding, then irradiate with UV following the chosen protocol.
Riboflavin toxicity was not detected. If used excessively, a minimum amount will accumulate in tissues, while the remaining will be briefly expelled. There were no adverse event reports with riboflavin use. Riboflavin can induce urine color change, if taken in large amount: this shouldn’t be considered a problem, since riboflavin does not cause adverse events.
Ribocross TE shouldn’t be used in cases of proven intolerance or hypersensibility to its components. Newborns treated for hyperbilirubinaemia could be sensitive to a riboflavin excess. Ribocross TE can be used during pregnancy or breastfeeding.
Ribocross TE must be conserved away from direct sunlight, at a temperature not over 30°C

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